Connection found between gene and depression
Home > News > Connection found between gene and depression
5:25 | 01/07/2012 | 31

Connection found between gene and depression

The breakthrough in research that has found the link between the gene and depression is likely to have a positive effect on the treatment of the increasing number...

Connection found between gene and depression

Prof. Son Hyeon Hanyang University

By Kim Bo-eunA research team discovered a close link between a gene in the brain and depression, opening the way for a more effectual remedy for the mental illness. The Ministry of Education, Science and Technology said Tuesday that the team led by Hanyang University biomedical science professor Son Hyeon found that a gene called neuritin plays an important role in regulating depression, affected by the activity of hippocampus neurons in the brain.The discovery was the result of four years of study on the behavior of white mice which developed depression. The hippocampus is the part of the brain that is involved in forming memories, organizing and storing information. The findings were published in the June edition of “Proceedings of the National Academy of Sciences (PNAS)”, a renowned international science journal.”It is significant that we have found a connection between depression and neuritin, which becomes more active stimulated by neurons”, said Son.”The information will be utilized when developing a new anti-depressant with a better efficacy”.According to the Health Insurance Review and Assessment Service, 510,000 Koreans currently have a depressive disorder. The figure is 20 percent up from 2007. Korea also has shown the highest suicide rate among member states of the Organization for Economic Cooperation and Development (OECD). Suicide is closely linked to depression. The breakthrough in research that has found the link between the gene and depression is likely to have a positive effect on the treatment of the increasing number of people suffering from depression.Depression is a mental disorder that is widespread among the public, regardless of age and gender. The disorder had been found to occur when the function and structure of the neuron in the hippocampus contracts.However, there had been no evidence on how the phenomenon was actually related to depression and what kind of effect the depression medicine had.Based on the fact that neuritin boosts the growth of neuritis, the team had set the hypothesis that the lack of neuritin causes depression and when a large amount is produced, the disorder is alleviated.The team had let the white mice develop chronic stress depression by providing two types of aversive stimuli daily for 35 days. The stimuli included trapping the mice in cold water and not giving food.The mice were found to be more immobile than other unaffected mice in situations in which they were trapped. This reflected that they had less will to try to escape, due to the depression that was developed as a result of stress.Then its researchers dissected the mice and found that the neuritin genes had decreased due to depression. They also found that neuritin had been restored to normal levels once anti-depressants such as Prozac had been injected into the mice.Depressive disorder develops as one shows symptoms such as a low mood and the loss of interest and pleasure in once enjoyable activities. It causes various cognitive, mental and physical symptoms and results in a decline in the ability to perform everyday activities.

Struggles of girl groups point to crises in K-pop

Struggles of girl groups point to crises in K-pop

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
SISTAR reveal which body part they would most like to have from the other members on "Entertainment Relay"

SISTAR reveal which body part they would most like to have from the other members on "Entertainment Relay"

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
Scholars" Village gives a Confucian education

Scholars" Village gives a Confucian education

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
Song Jae Rim and Kim So Eun wear couple outfits on "We Got Married"

Song Jae Rim and Kim So Eun wear couple outfits on "We Got Married"

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
2NE1 declines festival invites

2NE1 declines festival invites

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
Jessica shares pictures taken with Nicole Kidman, Chris Evans, Jay Chou, and more

Jessica shares pictures taken with Nicole Kidman, Chris Evans, Jay Chou, and more

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
Yoona Speaks Up About Her Relationship With Lee Seung Gi, Feels Apologetic Towards Her Members

Yoona Speaks Up About Her Relationship With Lee Seung Gi, Feels Apologetic Towards Her Members

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
Shin Hae-chul seriously ill

Shin Hae-chul seriously ill

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
Girl"s Day"s Yura sings Aladdin"s "A Whole New World" for Hong Jong Hyun on "We Got Married"

Girl"s Day"s Yura sings Aladdin"s "A Whole New World" for Hong Jong Hyun on "We Got Married"

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
Show me the way to the next whisky bar

Show me the way to the next whisky bar

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
Lim Tae Kyung & Paul Potts win with a splendid performance on "Immortal Song 2"

Lim Tae Kyung & Paul Potts win with a splendid performance on "Immortal Song 2"

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
Recovered relics

Recovered relics

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
B2ST test their friendship on "Entertainment Relay"

B2ST test their friendship on "Entertainment Relay"

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
Affordable Fashion: Park Shin Hye & Jung So Min “Miu Miu” Coats [Blog]

Affordable Fashion: Park Shin Hye & Jung So Min “Miu Miu” Coats [Blog]

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
Between scarlet mountains and the deep blue sea

Between scarlet mountains and the deep blue sea

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
Wardrobe Inspection: A K-Pop Halloween!

Wardrobe Inspection: A K-Pop Halloween!

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
TEEN TOP"s Niel and Changjo turn old-school into new-school on "Immortal Song 2"

TEEN TOP"s Niel and Changjo turn old-school into new-school on "Immortal Song 2"

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
Perfect autumn weather in Seoul

Perfect autumn weather in Seoul

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
Girl duo As One to comeback with "A Day Like Today"

Girl duo As One to comeback with "A Day Like Today"

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...
Epik High’s "Preview Night" private album premiere BTS video

Epik High’s "Preview Night" private album premiere BTS video

Girl group 2NE1 said yesterday that the group would not take part in any end-of-year music festival, even though it released its second studio album in February and stayed...